RELATED FACTORS FOR COLONIZATION BY Candida SPECIES IN THE ORAL CAVITY OF HIV-INFECTED INDIVIDUALS
نویسندگان
چکیده
UNLABELLED The colonization of the oral cavity is a prerequisite to the development of oropharyngeal candidiasis. AIMS The aims of this study were: to evaluate colonization and quantify Candida spp. in the oral cavity; to determine the predisposing factors for colonization; and to correlate the levels of CD4+ cells and viral load with the yeast count of colony forming units per milliliter (CFU/mL) in HIV-positive individuals treated at a University Hospital. Saliva samples were collected from 147 HIV patients and were plated on Sabouraud Dextrose Agar (SDA) and chromogenic agar, and incubated at 30 ºC for 72 h. Colonies with similar morphology in both media were counted and the result expressed in CFU/mL. RESULTS Of the 147 HIV patients, 89 had positive cultures for Candida spp., with a total of 111 isolates, of which C. albicans was the most frequent species (67.6%), and the mean of colonies counted was 8.8 × 10³ CFU/mL. The main predisposing factors for oral colonization by Candida spp. were the use of antibiotics and oral prostheses. The use of reverse transcriptase inhibitors appears to have a greater protective effect for colonization. A low CD4+ T lymphocyte count is associated with a higher density of yeast in the saliva of HIV patients.
منابع مشابه
Frequency of Candida species isolated from the Oral Cavity of HIV-Infected Patients referring to Behavioral disease Counseling Center of Isfahan in 2017-2018
Background and Aim: patients infected with HIV are susceptible to opportunistic infections such as candidiasis. In normal individuals, Candida spp. exist as normal flora of the mucous membranes. In this study we compared the frequencies of different species of Candida between HIV infected patients receiving anti-retroviral therapy (ART) and normal individuals. Materials and Methods: This case...
متن کاملمقایسه کلونیزاسیون کاندیدا در حفره دهانی استفاده کنندگان از دندان مصنوعی متحرک و افراد با دندانهای طبیعی: یک گزارش کوتاه
Background and Objective: Candida species are an important component of the resident microbial ecology of the oral cavity and are associated with various forms of oral candidosis when appropriate predisposing factors exist. Removable denture wearing is recognized as a predisposing factor for oral colonization by Candida species. The purpose of this study was to compare the colonization of ...
متن کاملA Comparative Evaluation of Oral Candida Carriage in HIV-Infected individuals and HIV Seronegative Healthy individuals in North Karnataka
Aim: Candida is one of the most common opportunistic fungi in HIV/AIDS cases. A detailed knowledge about oral candida carriage in HIV seropositive individuals is of paramount importance in the treatment of Oral Candidiasis (OC). In the present work, our aim was to determine and compare the candida carriage rate both in HIV infected and HIV non-infected healthy individuals along with knowing the...
متن کاملIdentification of Candida species in the oral cavity of diabetic patients
Background and Purpose: Diabetic patients are more susceptible to oral candidiasis infection than non-diabetics due to the factors promoting oral carriage of Candida. Several factors can increase colonization of Candida species in the oral cavity such as xerostomia, which reduces the salivary flow and is a salivary pH disorder. In the current study, we aimed to identify and compare the coloniza...
متن کاملThe Frequency of Candida and Staphylococcus Colonization in the Oral Cavity of the Elderly
Abstract Background and objectives: Poor oral hygiene in elderly people increases the colonization of opportunistic pathogens such as Candida and Staphylococci. The presence of yeasts and bacteria in the oral cavity of elderly people can be harmful and in certain conditions may cause oral and systemic infections. The general purpose of this study was to determine the oral health status, particu...
متن کامل